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2f-dck ,2-Fluorodeschloroketamine (also known as 2-Fl-2′-Oxo-PCM, Fluoroketamine and 2-FDCK) is a dissociative anesthetic. It is an analogue of ketamine where the chlorine group has been replaced by fluorine.Buy 2-FDCK online
2-fdck (also named Fluoroketamine) is very similar with MXPP. This product is intended for forensic and research applications.

2F-DCK (2-Fluorodeschloroketamine)

In recent years, the illicit drug market has seen the emergence of new psychoactive substances (NPS), also known as designer drugs, which aim to circumvent existing drug policies. One such substance that has gained attention is 2-Fluorodeschloroketamine (2F-DCK), a dissociative anesthetic closely related to ketamine. This article serves as a comprehensive guide to 2F-DCK, providing insights into its pharmacological properties, toxicokinetic profiles, and potential risks for drug users.

Section 1: Understanding 2F-DCK

• Introduction to 2F-DCK
  • Definition and molecular structure
  • Pharmacological effects and target receptors
  • Similarities and differences with ketamine
• Historical Context
  • Discovery and emergence in the drug market
  • Reported cases and prevalence
  • Legal status and drug scheduling
• Chemical Properties
  • Physical appearance and formulation
  • Analytical methods for detection and quantification
  • Stability and degradation pathways

Section 2: Pharmacokinetic Profiles

• Metabolic Fate
  • In vitro and in vivo metabolism studies
  • Identification of major metabolites
  • Enzymes involved in metabolism
• Toxicokinetic Parameters
  • Unbound fraction and protein binding
  • Hepatic clearance and in vitro-in vivo extrapolation (IVIVE)
  • Comparison with other dissociative ketamine analogues
• Routes of Administration and Absorption
  • Oral, intranasal, and intravenous administration
  • Absorption kinetics and bioavailability
  • Distribution and tissue accumulation

Section 3: Analytical Detection Methods

• Sample Collection and Preparation
  • Blood, urine, and hair as matrices
  • Extraction techniques and sample storage
  • Challenges and limitations in analysis
• Analytical Techniques
  • Gas chromatography-mass spectrometry (GC-MS)
  • Liquid chromatography-mass spectrometry (LC-MS)
  • High-resolution mass spectrometry (HRMS)
• Validation and Quality Control
  • Method validation parameters
  • Accuracy, precision, and limits of detection
  • Quality control measures and reference standards

Section 4: Pharmacological Effects and Adverse Reactions

• Psychoactive Effects
  • Dissociative and hallucinogenic properties
  • Duration and intensity of effects
  • Subjective experiences and user reports
• Potential Risks and Adverse Reactions
  • Acute toxicity and overdose symptoms
  • Drug interactions and contraindications
  • Long-term effects and potential addiction
• Medical and Therapeutic Applications
  • Anesthetic and analgesic properties
  • Potential for treating psychiatric disorders
  • Research and clinical trials

Section 5: Risk Assessment and Harm Reduction

• Public Health Concerns
  • Increased prevalence and availability
  • Challenges in regulation and control
  • Monitoring and surveillance efforts
• Harm Reduction Strategies
  • Education and awareness campaigns
  • Safer drug use practices
  • Access to drug treatment and support services
• International Perspectives and Policies
  • Global drug control conventions
  • Country-specific responses and legislation
  • Collaboration and information sharing

Section 6: Conclusion

In conclusion, 2-Fluorodeschloroketamine (2F-DCK) is a novel psychoactive substance that has gained popularity in the illicit drug market. Understanding its pharmacological properties, toxicokinetic profiles, and potential risks is crucial for public health professionals, law enforcement agencies, and healthcare providers. Further research is needed to fully comprehend the long-term effects and societal impact of this emerging substance. By staying informed and adopting harm reduction strategies, we can mitigate the potential risks associated with 2F-DCK and other designer drugs.

References (Include a list of properly formatted references)

Buy 2-Fluorodeschloroketamine online – Buy research chemical online
IUPAC name: 2-(2-Fluorophenyl)-2-methylamino-cyclohexanone
CAS Number: 111982-50-4
Formula: C13H16FNO
Molar mass: 221.28 g·mol−1

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2-Fluorodeschloroketamine (2-FDCK) as a substitute for ketamine has emerged among drug abusers in recent years.
However, 2-FDCK has not been controlled or regulated in many countries, which may be partly related to the lack of evidence on its abuse potential.

In this study, we evaluated the abuse potential of 2-FDCK via the tests of the conditioned place preference (CPP), locomotor sensitization, drug self-administration and drug discrimination using ketamine as a reference.

2-FDCK induced significant CPP at a minimum dose of 3 mg/kg in mice, an effect comparable with that of ketamine (3 mg/kg). Acute injections of 2-FDCK or ketamine at 30 mg/kg enhanced locomotor activity.

Repeated treatments with this dose of 2-FDCK and ketamine induced locomotor sensitization after withdrawal.

2-FDCK readily induced self-administration with 0.5 mg/kg/infusion, the same dose for ketamine, and induced the highest seeking response at 1 mg/kg. Drug discrimination test showed that 2-FDCK dose-dependently substitute for ketamine with comparable ED50 to ketamine in substitution testing.

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Taken together, these results strongly suggested that 2-FDCK has an abuse potential comparable with ketamine.

2-Fl-2′-Oxo-PCM (additionally referred to as 2-Fluorodeschloroketamine, 2-FDCK, and inaccurately as 2-Fluroketamine, Fluoroketamine, and 2-FK) is a lesser-acknowledged novel dissociative substance of the arylcyclohexylamine class. It is chemically just like ketamine and deschloroketamine . It is notion to behave as an NMDA receptor antagonist, despite the fact that studies are presently limited. 2-fdck for sale usa

The origins of 2F-DCK aren’t well-documented. It seems to have first grown to be had on the market on the net studies chemical marketplace in 2017, wherein it become advertised as a prison substitute for ketamine. It become launched after the hit advent of a comparable ketamine analog, deschloroketamine. buy 2-fdck

Subjective consequences consist of sedation, motor management loss, ache relief, inner hallucinations, conceptual thinking, euphoria, and dissociation. Dissociation is a complicated intellectual country characterized via way of means of perceptual distortions and emotions of detachment from the surroundings and one’s self. 2F-DCK’s consequences are stated to be just like the ones of ketamine. 2 fdck for sale

Like ketamine, 2F-DCK’s consequences are noticeably dose-dependent, with decreased doses generating alcohol-like intoxication and better doses generating hallucinogenic out-of-frame states (additionally referred to as a “k-hole”).

Limited statistics exist on the pharmacology, metabolism, or toxicity of 2-FDCK. It has an incredibly short record of human use. It is strongly cautioned to apply damage discount practices if the use of this substance. buy 2-fdck us

Chemistry of 2 fdck — 2-fdck buy online

2-Fluorodeschloroketamine, or 2-(2-Fluorophenyl)-2-methylamino-cyclohexanone, is classified as an arylcyclohexylamine drug. Arylcyclohexylamines pills are named for his or her systems which consist of a cyclohexane ring certain to be a fragrant ring alongside an amine group. high purity 2fdck

Buy 2-FDCK online/buy 2 fdck .2-FDCK consists of a phenyl ring bonded to a cyclohexane ring substituted with a ketone group (cyclohexanone). An amino methyl chain (-N-CH3) is certain to the adjoining alpha carbon of the cyclohexanone ring. Additionally, the phenyl ring is replaced in R2 with a fluorine group. 2-fdck for sale

2-Fluorodescholoroketamine is a chiral molecule and is frequently produced as a racemate. Des- is a prefix utilized in chemistry to indicate the absence of a useful group (in this case “chloro”) consequently 2-FDCK is known for holding a fluorine substitution at its phenyl ring instead of the chlorine that’s observed in ketamine. 2 fdck usa