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MDMA crystals was discovered in 1912 and first saw use in underground psychotherapy circles in the 1970s. In the 1980s, MDMA spread into nightlife and rave culture and was subsequently banned. By 2014, MDMA was estimated to be one of the most popular recreational drugs used in the world, alongside cocaine and cannabis. Researchers are investigating whether MDMA may assist in treatment-resistant posttraumatic stress disorder (PTSD), social anxiety in autistic adults, and anxiety in those with life-threatening illness.cancion mdma
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Crystals that are 84% pure MDMA – the chemical name for ecstasy – are manufactured by Breaking Bad-style scientists and sold for up to £4,300 a batch.
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Ecstasy is a synthetic substance commonly known as MDMA, although the latter term has now been generalised to cover a wide range of other substances.
Originally developed in 1912 by the Merck chemical company, it was never marketed as such. Although proposed as an aid to psychiatric counselling, therapeutic use is extremely limited. Illicit MDMA is normally seen as tablets, many of which are manufactured in Europe.
It acts as a central nervous system (CNS) stimulant and has a weak hallucinogenic property more accurately described as increased sensory awareness. Ecstasy is under international control.
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Ecstasy is an abbreviation for methylenedioxy–methylamphetamine. The formal (IUPAC) name is N-methyl-1-(3,4-methylenedioxyphenyl)propan-2-amine, but MDMA (CAS-42542-10-09) is commonly known as 3,4-methylenedioxymethamphetamine or methylenedioxy-methylamfetamine. Other chemical names include N,α-dimethyl-3,4-methylenedioxyphenethylamine or, less usually, N-methyl-1-(1,3-benzodioxol-5-yl)-2-propanamine. MDMA is a member of the larger group of ring-substituted phenethylamines. As with other phenethylamines, and like its close relative methamphetamine, MDMA also exists in two enantiomeric forms (R and S). MDMA crystals
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Whereas phenethylamines without ring substitution usually behave as stimulants, ring substitution (as in MDMA) leads to a modification in the pharmacological properties. MDMA crystals
Ingestion of MDMA causes euphoria, increased sensory awareness and mild central stimulation. It is less hallucinogenic than its lower homologue, methylenedioxyamphetamine (MDA).
The terms empathogenic and entactogenic have been coined to describe the socialising effects of MDMA. Following ingestion, most of the dose of Ecstasy is excreted in the urine unchanged.
Major metabolites are 3,4-methylenedioxyamphetamine (MDA) and O-demethylated compounds.
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Following a dose of 75 mg, the maximum plasma concentration of around 0.13 mg/L is reached within two hours. The plasma half-life is 6–7 hours. MDMA crystals
In animals, Ecstasy causes neurotoxicity, as evidenced by anatomical changes in axon structure and a persisting reduction in brain serotonin levels. MDMA crystals
The significance of these findings to human users is still unclear, although cognitive impairment is associated with MDMA use.
Some of the pharmacodynamic and toxic effects of MDMA vary, depending on which enantiomer is used.
However, almost all illicit MDMA exists as a racemic mixture. Fatalities following a dose of 300 mg have been noted, but toxicity depends on many factors, including individual susceptibility and the circumstances in which MDMA is used. MDMA crystals
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There are four principal precursors which can be used in the manufacture of Ecstasy and related drugs: safrole, isosafrole, piperonal and 3,4-methylenedioxyphenyl-2-propanone (PMK).
Safrole is the key starting material in so far as the other three can be synthesised from it.
In the original Merck patent of 1914, safrole was reacted with hydrobromic acid to form bromosafrole, which was converted to MDMA using methylamine. MDMA crystals
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Many illicit syntheses start with PMK and use either the Leuckart route or various reductive aminations including the aluminium foil method.
All of these methods produce racemic Ecstasy. The four precursors noted above are listed in Table I of the United Nations 1988 Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances.
The corresponding EU legislation is set out in Council Regulation (EEC) No 3677/90 (as later amended), which governs trade between the EU and third countries.
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Buy Ecstasy Online Australia.MDMA (3-4 methylenedioxymethamphetamine) is a synthetic, psychoactive drug with a chemical structure similar to the stimulant methamphetamine and the hallucinogen mescaline. MDMA crystals
MDMA is an illegal drug that acts as both a stimulant and psychedelic, producing an energizing effect, as well as distortions in time and perception and enhanced enjoyment from tactile experiences’ Ecstasy Online Australia. MDMA crystals
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Ecstasy is a synthetic, psychoactive medicine chemically similar to the methamphetamine stimulant and mescalin hallucinogen. It is an illicit drug that acts both as a psychedelic and stimulator, creating energy-effects, hallucinations and enhancing enjoyment from tactile sensation of time and perception. MDMA crystals
Their primary effect is on neurons in the brain which communicate with other neurons using chemical serotonin. In the regulation of the mood, aggression, sexual behavior, sleep and pain, the serotonin system is an important factor. MDMA crystals
The use of ESCTASY in patients suffering from PPSD was discussed in a small 2018 report released by The Lancet Psychiatry. Investigators gave 22 veterans, three firefighters and one police officer with PTSD three separate doses of ESCTASY. 23% used ecstasy before among the participants. MDMA crystals
The use of ESCTASY was also correlated with psychotherapy. One month after the second session a larger proportion of high-dose groups in contrast with the low-dose category do not meet PTSD assessment requirements anymore.
16 out of 26 participants (62%) were not affected by PTSD after one year, but two had been diagnosed with new PTSD. Additional psychiatric treatment was also taken by 12 patients. Not all experts were convinced, however.
With this small community, long-term protection could not be assured, and a population already at risk for certain severe outcomes risks of addiction and suicide. MDMA crystals
Researchers note that larger studies in phase 3 should be done, but PSTD researchers could NOT reproduce such data with the use of ESCTASY alone. MDMA crystals
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Individuals who use ESCTASY usually take it as a pill or tablet, but they drink the liquid or snort the Individu
The famous term Molly (“molecular” slang) also applied to the so-called “clean” crystalline powder type of ESCTASY, which is usually sold in capsules. MDMA crystals
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